Tim Scully is best known in the psychedelic underground for his work in the production of LSD from 1966 to 1969, for which he was indicted in 1973 and convicted in 1974. His best known product, dubbed "Orange Sunshine", was considered the standard for quality LSD in 1969. Scully worked with Owsley Stanley and Nick Sand in the late 1960s. During his LSD manufacturing career, Scully worked in four labs (documented in his 1973 trial):

• With Bear (Owsley) in a Pt. Richmond, CA lab in 1966, as his apprentice
• With Bear in a first Denver lab (set up by Scully) in 1967
• On his own in a second Denver lab in 1968
• In a Windsor, CA lab, which he set up in 1969 (where Orange Sunshine was made and where Nick Sand learned the process)

Scully had his work "busted" twice — once in 1969 for the 1968 Denver lab (the search was eventually ruled illegal in 1972) and once in 1973 for the 1969 Windsor lab conspiracy (which resulted in a 20 year sentence). Scully spent his time in prison helping with computers and improving communications for disabled prisoners.

His entire life, Tim Scully has been interested in cutting edge technology and computers. As a teen in 1958, he earned an honorable mention at a San Francisco Bay Area science fair for designing and building a small computer. He later received recognition for building a small linear accelerator pictured in a 1961 edition of the Oakland Tribune. He was trying to make gold atoms from mercury.

Scully has been a pilot much of his adult life and has worked in biofeedback and interface systems for people with disabilities. He has published eight articles on the topic of biofeedback and as many on technical computer topics. He retired from his years of work with Autodesk in 2005 and is currently researching a book on the underground history of LSD.